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  • About Maze
    • Meet the Experts
    • Insurance Coverage
    • Our Published Studies
    • Additional Resources
    • In the News
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  • TRT/Low T
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  • Sexual Health
    • Low Libido
    • Premature Ejaculation
    • Delayed Ejaculation
    • Peyronie’s Disease
    • Chronic Pelvic Pain Syndrome
    • Gay/Bisexual Men’s Sexual Health
    • Penile Rehabilitation
    • Sexual Education
  • Reproductive Health
    • Male Infertility
    • Azoospermia Treatment
    • Semen Analysis
    • Extended Sperm Search & Microfreeze (ESSM)
    • Sperm Mapping
    • Sperm Extraction Procedure
    • Varicoceles/Varicocelectomy
    • Epididymal Obstruction
    • Sperm Banking
    • Vasectomy
  • Better Sex Blog
Contact Us
logo
  • About Maze
    • Meet the Experts
    • Insurance Coverage
    • Our Published Studies
    • Additional Resources
    • In the News
    • Join Our Team
  • TRT/Low T
  • ED
  • Sexual Health
    • Low Libido
    • Premature Ejaculation
    • Delayed Ejaculation
    • Peyronie’s Disease
    • Chronic Pelvic Pain Syndrome
    • Gay/Bisexual Men’s Sexual Health
    • Penile Rehabilitation
    • Sexual Education
  • Reproductive Health
    • Male Infertility
    • Azoospermia Treatment
    • Semen Analysis
    • Extended Sperm Search & Microfreeze (ESSM)
    • Sperm Mapping
    • Sperm Extraction Procedure
    • Varicoceles/Varicocelectomy
    • Epididymal Obstruction
    • Sperm Banking
    • Vasectomy
  • Better Sex Blog
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  • Westchester: (914) 997-4100
  • New York City: (646) 380-2600
  • Connecticut: (203) 831-9900
  • New Jersey: (973) 472-0600

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Management

Back to TRT
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The Full Picture: How TRT Improves Your Body, Bones, and Brain

At Maze Men’s Health, we treat the whole man, not just hormone levels. Our approach to testosterone replacement therapy (TRT) integrates medical, metabolic, and mental health so you can feel stronger, sharper, and more in control of your life.

Many men who come to us struggle with fatigue, weight gain, poor sleep, anxiety, or brain fog—issues often under-diagnosed or mismanaged elsewhere. Through a comprehensive evaluation and a customized care plan, we connect the dots between Low T, metabolism, and mental health.
Our programs often include TRT, GLP-1 weight loss medications, DEXA bone and body scans, and targeted lifestyle or psychiatric support—a full-spectrum approach to restoring vitality.

Body: Weight, Muscle & Metabolism

Low testosterone makes fat loss difficult and muscle maintenance nearly impossible, even with disciplined diet and exercise. Men often experience low energy, belly fat gain, and minimal workout results—especially when using GLP-1 medications like semaglutide or tirzepatide, which can reduce lean mass if not managed correctly.

TRT helps reverse that spiral. By restoring hormonal balance, testosterone:

  • Boosts muscle protein synthesis and reduces breakdown
  • Raises basal metabolic rate (BMR) by increasing muscle mass
  • Enhances VO₂ max and workout recovery
  • Improves fat oxidation, particularly abdominal fat

When paired with GLP-1 therapy, TRT protects against muscle loss, supports strength, and enhances energy—helping you maintain long-term results safely.

Summary: TRT builds and preserves muscle, boosts metabolism, improves exercise response, and prevents the muscle loss common with weight loss drugs.

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Bones: Strength, Density & Longevity

Bone loss is a hidden consequence of Low T—and not just a women’s issue. Up to one in four men over 50 will experience a fracture related to osteoporosis, often without knowing their bone density is declining.

Testosterone is crucial for bone formation and maintenance. It stimulates bone-building cells (osteoblasts), preserves bone density in the hips and spine, and reduces fracture risk.

At Maze, we use DEXA scans to measure and track bone mineral density (BMD) over time. Early detection allows us to reverse or stabilize bone loss before it leads to injury.

Summary: TRT improves bone strength, increases density, and works synergistically with exercise to protect long-term mobility and independence.

Brain: Mood, Sleep & Cognitive Clarity

Low testosterone doesn’t just drain physical energy—it impacts mental and emotional health. Men with Low T often report depression, anxiety, poor focus, and restless sleep.

TRT helps restore mental balance and clarity by:

  • Boosting dopamine and serotonin for motivation and calm
  • Regulating GABA and lowering stress hormone (cortisol) levels
  • Supporting memory and focus through hippocampal and prefrontal cortex pathways
  • Improving circadian rhythm for deeper, more restorative sleep

Men often describe feeling “like themselves again”—more focused, even-tempered, and motivated. TRT also complements psychiatric medications, sometimes allowing for lower doses or better outcomes.

Summary: TRT enhances mood, sleep quality, focus, and resilience—helping you perform better at work, in relationships, and in life.

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Why Choose Maze

  • Integrated Expertise: Specialists in men’s hormonal, sexual, and psychological health
  • Comprehensive Approach: Seamless coordination of TRT, GLP-1s, and lifestyle optimization
  • Proven Results: Over 30 years of experience helping men rebuild strength, focus, and confidence

Maze Men’s Health delivers science-based, medically supervised testosterone therapy that strengthens your body, bones, and brain—so you can live sharper, stronger, and longer.

TRT Management: Safety, Risks & Real Results

A Balanced, Evidence-Based Approach

At Maze Men’s Health, we believe in informed, personalized care—not scare tactics. Despite what you may have read online, decades of research show that testosterone replacement therapy (TRT) does not increase the risk of prostate cancer or heart disease when properly managed. In fact, maintaining healthy testosterone levels can improve cardiovascular, sexual, and overall health.

The two most common questions we hear are:

  • Will TRT cause prostate issues or prostate cancer?
  • Does TRT raise my risk for heart attack or stroke?

Here’s what the science—and our experience—say.

img a balanced evidence based approach

Prostate Health and TRT

The idea that testosterone “feeds” prostate cancer is outdated. Studies show:

  • Men with higher natural testosterone do not have higher prostate cancer rates.
  • Low testosterone may actually increase risk.
  • TRT within healthy ranges does not enlarge the prostate or raise PSA in a harmful way.

The modern “saturation model” explains that once testosterone receptors are full (around a level of 300), extra testosterone doesn’t stimulate more prostate growth—like a sponge that can’t absorb more water.

Leading urology centers now safely offer TRT even after prostate cancer treatment or during active surveillance.

Heart Health and TRT

Newer studies confirm that TRT can improve cardiovascular health. Men treated for Low T often experience:
  • Better motivation and energy to exercise
  • Lower body fat and improved cholesterol, blood pressure, and blood sugar
  • Increased muscle mass, libido, and mood

Earlier reports linking TRT to heart attacks were based on flawed studies—later retracted. Modern data shows well-monitored TRT supports heart health.

Possible Side Effects (and How We Manage Them)

With expert oversight, side effects are rare and manageable:

  • Fluid Retention: Usually mild and short-lived.
  • Fertility Impact: TRT can suppress sperm production; Maze offers sperm banking and alternatives like clomiphene or HCG for men planning families.
  • Sleep Apnea: Typically improves with weight loss and fitness gains on TRT.
  • Estrogen Increase: Managed with aromatase inhibitors if needed.
  • Higher Red Blood Cell Count: Monitored through regular labs and treated with simple blood donation if necessary.

Safe, Long-Term Management

TRT works best with consistent follow-up. At Maze, we monitor hormone levels, hematocrit, and overall well-being every few months to ensure therapy stays safe and effective. Most men thrive at high-normal testosterone levels, where energy, focus, and vitality are optimized.

TRT isn’t a quick fix—it’s a commitment to feeling and functioning your best under expert medical care.

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Maze Men’s Sexual & Reproductive Health

Led by Michael A. Werner, MD, a board-certified urologist specializing in sexual and reproductive health, Maze has always focused on making a difference in people’s lives. This approach — one of compassion, medical sophistication and an openness to new techniques — extends to each individual area of our practice.

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Westchester

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    New York, NY 10017
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